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Beilstein J. Org. Chem. 2019, 15, 2812–2821, doi:10.3762/bjoc.15.274
Graphical Abstract
Figure 1: Fluoro-AB derivatives and spectra. Structures of 4FAB-diamides [13] cis and trans configurations, and t...
Scheme 1: Synthesis of 4FABTA. a) Reagents and conditions: (a) 3-Butynol, PdCl2(PPh3)2, CuI, THF, rt, 93%; (b...
Figure 2: Photochemistry of 4FABTA (2), and thermodynamic stability in physiological buffer. a) Trans–cis pho...
Figure 3: Reaction of t-4FABTA (1) with thiols, and thermal stability of initial conjugate. a) Chemical react...
Figure 4: Testing photo-antagonism of 1 with genetically tagged nicotinic acetylcholine receptors. Currents f...
Figure 5: Photopharmacology with 4FABTA (2). Currents from neurons in the medial habenula in acutely isolated...
Beilstein J. Org. Chem. 2013, 9, 1194–1201, doi:10.3762/bjoc.9.135
Figure 1: Examples of naturally occurring quinazoline alkaloids.
Figure 2: Different approaches to the synthesis of quinazoline alkaloid structures.
Scheme 1: Oxidation of other aminal systems.